{"id":120556,"date":"2024-11-12T19:09:07","date_gmt":"2024-11-12T17:09:07","guid":{"rendered":"https:\/\/prohoster.info\/blog\/novosti-interneta\/deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov"},"modified":"2024-11-12T19:09:07","modified_gmt":"2024-11-12T17:09:07","slug":"deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov","status":"publish","type":"post","link":"https:\/\/prohoster.info\/cs\/blog\/news\/deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov","title":{"rendered":"DeepMind zve\u0159ejnil k\u00f3d AlphaFold 3, AI syst\u00e9m modelov\u00e1n\u00ed struktury protein\u016f","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

Spole\u010dnost Google DeepMind zve\u0159ejnila zdrojov\u00e9 k\u00f3dy strojov\u00e9ho u\u010den\u00ed AlphaFold 3, navr\u017een\u00e9 pro predikci trojrozm\u011brn\u00e9 struktury protein\u016f a modelov\u00e1n\u00ed interakc\u00ed protein\u016f s jin\u00fdmi typy molekul. Za v\u00fdvoj algoritm\u016f strojov\u00e9ho u\u010den\u00ed, implementovan\u00fdch ve druh\u00e9 verzi AlphaFold, byla letos ud\u011blena Nobelova cena za chemii. N\u00e1stroje souvisej\u00edc\u00ed s AlphaFold 3 jsou naps\u00e1ny v Pythonu a C++ a jsou distribuov\u00e1ny pod licenc\u00ed CC BY-NC-SA 4.0. Natr\u00e9novan\u00e9 modely jsou poskytov\u00e1ny na z\u00e1klad\u011b u\u017eivatelsk\u00e9 dohody. Byla tak\u00e9 spu\u0161t\u011bna server<\/a>online platforma, kter\u00e1 umo\u017e\u0148uje experimentovat s AlphaFold 3. <\/p>\n

Model, kter\u00e1 byla vy\u0161kolena na z\u00e1klad\u011b sb\u00edrky popis\u016f struktur v\u0161ech zn\u00e1m\u00fdch protein\u016f a aminokyselinov\u00fdch sekvenc\u00ed, \u0159e\u0161\u00ed probl\u00e9m skl\u00e1d\u00e1n\u00ed b\u00edlkovin a umo\u017e\u0148uje p\u0159edpov\u00eddat trojrozm\u011brnou strukturu nov\u00fdch b\u00edlkovin s p\u0159esnost\u00ed, kter\u00e1 alespo\u0148 nen\u00ed hor\u0161\u00ed ne\u017e laboratorn\u00ed anal\u00fdza, a p\u0159i hodnocen\u00ed interakc\u00ed b\u00edlkovin s jin\u00fdmi typy molekul v\u00fdrazn\u011b p\u0159ekra\u010duje st\u00e1vaj\u00edc\u00ed metody p\u0159edpov\u011bdi. T\u0159et\u00ed verze modelu AlphaFold se vyzna\u010duje vyu\u017eit\u00edm nov\u00e9 architektury \u201ePairformer\u201c, kter\u00e1 rozv\u00edj\u00ed my\u0161lenku architektury \u201etransformer\u201c. <\/p>\n

Na rozd\u00edl od AlphaFold 2 nov\u00e1 verze nen\u00ed omezena na proteiny slo\u017een\u00e9 z jedn\u00e9 polypeptidov\u00e9 \u0159et\u011bzce a m\u016f\u017ee b\u00fdt pou\u017eita pro predikci proteinov\u00fdch komplex\u016f s DNA a RNA, stejn\u011b jako pro modelov\u00e1n\u00ed modifikovan\u00fdch variant t\u011bchto molekul. Na vstupu se AlphaFold p\u0159eb\u00edr\u00e1 seznam molekul a na v\u00fdstupu se generuje spole\u010dn\u00e1 3D struktura, kter\u00e1 ur\u010duje nejpravd\u011bpodobn\u011bj\u0161\u00ed interakce uveden\u00fdch molekul. <\/p>\n

Z praktick\u00e9ho hlediska lze AlphaFold 3 pou\u017e\u00edt pro v\u00fdvoj l\u00e9k\u016f a l\u00e9\u010debn\u00fdch metod a tak\u00e9 pro vytv\u00e1\u0159en\u00ed nov\u00fdch protein\u016f. Nap\u0159\u00edklad pomoc\u00ed AlphaFold byl navr\u017een protein schopn\u00fd se p\u0159ichytnout na ur\u010dit\u00e9 rakovinn\u00e9 bu\u0148ky, co\u017e m\u016f\u017ee b\u00fdt vyu\u017eito v onkologick\u00e9 terapii nov\u00e9 generace. AlphaFold se tak\u00e9 aktivn\u011b pou\u017e\u00edv\u00e1 p\u0159i studiu interakc\u00ed protil\u00e1tek s proteiny k pochopen\u00ed lidsk\u00e9 imunitn\u00ed reakce a vytv\u00e1\u0159en\u00ed nov\u00fdch protil\u00e1tek.
\n
Zdroj: opennet.ru<\/a> <\/p>","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

\u041a\u043e\u043c\u043f\u0430\u043d\u0438\u044f Google DeepMind \u043e\u043f\u0443\u0431\u043b\u0438\u043a\u043e\u0432\u0430\u043b\u0430 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u0435 \u0442\u0435\u043a\u0441\u0442\u044b \u0441\u0438\u0441\u0442\u0435\u043c\u044b \u043c\u0430\u0448\u0438\u043d\u043d\u043e\u0433\u043e \u043e\u0431\u0443\u0447\u0435\u043d\u0438\u044f AlphaFold 3, \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u043d\u043e\u0439 \u0434\u043b\u044f \u043f\u0440\u0435\u0434\u0441\u043a\u0430\u0437\u0430\u043d\u0438\u044f \u0442\u0440\u0451\u0445\u043c\u0435\u0440\u043d\u043e\u0439 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u044b \u0431\u0435\u043b\u043a\u043e\u0432 \u0438 \u043c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f \u0431\u0435\u043b\u043a\u043e\u0432 \u0441 \u0434\u0440\u0443\u0433\u0438\u043c\u0438 \u0442\u0438\u043f\u0430\u043c\u0438 \u043c\u043e\u043b\u0435\u043a\u0443\u043b. \u0417\u0430 \u0441\u043e\u0437\u0434\u0430\u043d\u0438\u0435 \u0430\u043b\u0433\u043e\u0440\u0438\u0442\u043c\u043e\u0432 \u043c\u0430\u0448\u0438\u043d\u043d\u043e\u0433\u043e \u043e\u0431\u0443\u0447\u0435\u043d\u0438\u044f, \u0440\u0435\u0430\u043b\u0438\u0437\u043e\u0432\u0430\u043d\u043d\u044b\u0445 \u0432\u043e \u0432\u0442\u043e\u0440\u043e\u0439 \u0432\u0435\u0440\u0441\u0438\u0438 AlphaFold, \u0432 \u044d\u0442\u043e\u043c \u0433\u043e\u0434\u0443 \u043f\u0440\u0438\u0441\u0443\u0436\u0434\u0435\u043d\u0430 \u041d\u043e\u0431\u0435\u043b\u0435\u0432\u0441\u043a\u0430\u044f \u043f\u0440\u0435\u043c\u0438\u044f \u043f\u043e \u0445\u0438\u043c\u0438\u0438. \u0421\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0439 \u0441 AlphaFold 3 \u0438\u043d\u0441\u0442\u0440\u0443\u043c\u0435\u043d\u0442\u0430\u0440\u0438\u0439 \u043d\u0430\u043f\u0438\u0441\u0430\u043d \u043d\u0430 Python \u0438 C++, \u0438 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u044f\u0435\u0442\u0441\u044f […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[702],"tags":[],"class_list":["post-120556","post","type-post","status-publish","format-standard","hentry","category-news"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\n","aioseo_head_json":{"title":"\ud83e\udd47DeepMind zp\u0159\u00edstupnil k\u00f3d AlphaFold 3, AI syst\u00e9mu pro modelov\u00e1n\u00ed struktury b\u00edlkovin | ProHoster","description":"Spole\u010dnost Google DeepMind zve\u0159ejnila zdrojov\u00e9 k\u00f3dy syst\u00e9mu strojov\u00e9ho u\u010den\u00ed AlphaFold 3, ur\u010den\u00e9ho k p\u0159edpov\u00edd\u00e1n\u00ed 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\u0442\u0438\u043f\u0430\u043c\u0438.","og:url":"https:\/\/prohoster.info\/cs\/blog\/news\/deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov","og:image":"https:\/\/prohoster.info\/wp-content\/uploads\/2021\/11\/logo-350.jpg","og:image:secure_url":"https:\/\/prohoster.info\/wp-content\/uploads\/2021\/11\/logo-350.jpg","og:image:width":350,"og:image:height":350,"article:published_time":"2024-11-12T17:09:07+00:00","article:modified_time":"2024-11-12T17:09:07+00:00","article:publisher":"https:\/\/www.facebook.com\/prohoster","article:author":"https:\/\/www.facebook.com\/prohoster"},"aioseo_meta_data":{"post_id":"120556","title":null,"description":null,"keywords":null,"keyphrases":null,"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":null,"og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":null,"robots_max_videopreview":null,"robots_max_imagepreview":"large","priority":null,"frequency":null,"local_seo":null,"seo_analyzer_scan_date":"2026-01-23 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