{"id":120556,"date":"2024-11-12T19:09:07","date_gmt":"2024-11-12T17:09:07","guid":{"rendered":"https:\/\/prohoster.info\/blog\/novosti-interneta\/deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov"},"modified":"2024-11-12T19:09:07","modified_gmt":"2024-11-12T17:09:07","slug":"deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov","status":"publish","type":"post","link":"https:\/\/prohoster.info\/et\/blog\/news\/deepmind-otkryl-kod-alphafold-3-ai-sistemy-modelirovaniya-struktury-belkov","title":{"rendered":"DeepMind avalikustas AlphaFold 3 koodi, tehisintellekti s\u00fcsteemi, mis modelleerib valkude struktuuri","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

Google DeepMind on avaldanud AlphaFold 3 masin\u00f5ppes\u00fcsteemi l\u00e4htekoodid, mis on m\u00f5eldud valkude kolmem\u00f5\u00f5tmelise struktuuri ennustamiseks ja valkude interaktsioonide modelleerimiseks teiste molekulit\u00fc\u00fcpidega. Masin\u00f5ppetehnoloogiate loomise eest, mis on rakendatud AlphaFoldi teises versioonis, on sel aastal antud keemia Alfred Nobeli auhind. AlphaFold 3-ga seotud t\u00f6\u00f6riist on kirjutatud Pythonis ja C++-s ning levis CC BY-NC-SA 4.0 litsentsi alusel. Treenitud mudeleid pakutakse kasutaja lepingu alusel. Eraldi on v\u00e4lja t\u00f6\u00f6tatud server<\/a>, mis v\u00f5imaldab AlphaFold 3-ga eksperimenteerida veebire\u017eiimis. <\/p>\n

Mudel, mis on koolitatud k\u00f5igi tuntud valkude ja aminohapete j\u00e4rjestuste struktuuride kirjelduse kogumi p\u00f5hjal, lahendab valgu kokkupanemise probleemi ja v\u00f5imaldab prognoosida uute valkude kolmem\u00f5\u00f5tmelist struktuuri v\u00e4hemalt sama t\u00e4psusega nagu laboratoorsed anal\u00fc\u00fcsid, samas kui valkude koostoime hindamisel teiste molekulit\u00fc\u00fcpidega \u00fcletab see olemasolevaid prognoosimismeetodeid oluliselt. Kolmas AlphaFold mudeli versioon eristub uue arhitektuuri 'Pairformer' kasutuselev\u00f5tuga, mis arendab edasi 'transformeri' arhitektuuri ideed. <\/p>\n

Erinevalt AlphaFold 2-st ei piirdu uus versioon \u00fcksikute pol\u00fcpeptiidahelatega, vaid seda saab kasutada valkude komplekside ennustamiseks DNA ja RNA-ga ning modifitseeritud versioonide modelleerimiseks. AlphaFoldile edastatakse molekulide loetelu ja v\u00e4ljundina genereeritakse \u00fchine 3D-struktuur, mis m\u00e4\u00e4rab \u00e4ra t\u00f5en\u00e4olisema interaktsiooni antud molekulide vahel. <\/p>\n

Praktilisest k\u00fcljest saab AlphaFold 3-d kasutada ravimite ja ravimeetodite v\u00e4ljat\u00f6\u00f6tamiseks, samuti uute valkude loomiseks. N\u00e4iteks on AlphaFoldi abil projekteeritud valk, mis suudab kinnituda teatud v\u00e4hirakkudele, mida saab kasutada uue p\u00f5lvkonna v\u00e4hivastases ravis. AlphaFoldi kasutatakse ka antikehade ja valkude interaktsioonide uurimiseks, et m\u00f5ista inimese immuunvastust ja luua uusi antikehi.
\n
Allikas: opennet.ru<\/a> <\/p>","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

\u041a\u043e\u043c\u043f\u0430\u043d\u0438\u044f Google DeepMind \u043e\u043f\u0443\u0431\u043b\u0438\u043a\u043e\u0432\u0430\u043b\u0430 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u0435 \u0442\u0435\u043a\u0441\u0442\u044b \u0441\u0438\u0441\u0442\u0435\u043c\u044b \u043c\u0430\u0448\u0438\u043d\u043d\u043e\u0433\u043e \u043e\u0431\u0443\u0447\u0435\u043d\u0438\u044f AlphaFold 3, \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u043d\u043e\u0439 \u0434\u043b\u044f \u043f\u0440\u0435\u0434\u0441\u043a\u0430\u0437\u0430\u043d\u0438\u044f \u0442\u0440\u0451\u0445\u043c\u0435\u0440\u043d\u043e\u0439 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u044b \u0431\u0435\u043b\u043a\u043e\u0432 \u0438 \u043c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f \u0431\u0435\u043b\u043a\u043e\u0432 \u0441 \u0434\u0440\u0443\u0433\u0438\u043c\u0438 \u0442\u0438\u043f\u0430\u043c\u0438 \u043c\u043e\u043b\u0435\u043a\u0443\u043b. \u0417\u0430 \u0441\u043e\u0437\u0434\u0430\u043d\u0438\u0435 \u0430\u043b\u0433\u043e\u0440\u0438\u0442\u043c\u043e\u0432 \u043c\u0430\u0448\u0438\u043d\u043d\u043e\u0433\u043e \u043e\u0431\u0443\u0447\u0435\u043d\u0438\u044f, \u0440\u0435\u0430\u043b\u0438\u0437\u043e\u0432\u0430\u043d\u043d\u044b\u0445 \u0432\u043e \u0432\u0442\u043e\u0440\u043e\u0439 \u0432\u0435\u0440\u0441\u0438\u0438 AlphaFold, \u0432 \u044d\u0442\u043e\u043c \u0433\u043e\u0434\u0443 \u043f\u0440\u0438\u0441\u0443\u0436\u0434\u0435\u043d\u0430 \u041d\u043e\u0431\u0435\u043b\u0435\u0432\u0441\u043a\u0430\u044f \u043f\u0440\u0435\u043c\u0438\u044f \u043f\u043e \u0445\u0438\u043c\u0438\u0438. \u0421\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0439 \u0441 AlphaFold 3 \u0438\u043d\u0441\u0442\u0440\u0443\u043c\u0435\u043d\u0442\u0430\u0440\u0438\u0439 \u043d\u0430\u043f\u0438\u0441\u0430\u043d \u043d\u0430 Python \u0438 C++, \u0438 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u044f\u0435\u0442\u0441\u044f […]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[702],"tags":[],"class_list":["post-120556","post","type-post","status-publish","format-standard","hentry","category-news"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\n","aioseo_head_json":{"title":"\ud83e\udd47DeepMind avas koodi AlphaFold 3, valkude struktuuri modelleerimise AI-s\u00fcsteem | ProHoster","description":"Google DeepMind on avaldanud AlphaFold 3 masin\u00f5ppes\u00fcsteemi l\u00e4htekoodid, mis on m\u00f5eldud valkude kolmem\u00f5\u00f5tmelise struktuuri ennustamiseks ja valkude interaktsioonide modelleerimiseks teiste 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