Niaj hnub no, peb tuaj yeem nkag mus rau txhua tus tib neeg txoj kev paub los ntawm cov khoos phis tawj me me hauv peb lub hnab ris. Tag nrho cov ntaub ntawv no yuav tsum tau muab khaws cia rau qhov chaw, tab sis cov servers loj loj siv ntau qhov chaw ntawm lub cev thiab xav tau ntau lub zog. Cov kws tshawb fawb Harvard tau tsim cov txheej txheem tshiab rau kev nyeem ntawv thiab sau cov ntaub ntawv siv cov organic molecules uas tuaj yeem ua haujlwm ruaj khov thiab ua haujlwm tau ntau txhiab xyoo.
DNA yog nkag siab txog cov cuab yeej khaws cia cov ntaub ntawv hauv lub ntiaj teb ntuj-nws tuaj yeem khaws ntau cov ntaub ntawv hauv cov khoom me me thiab ruaj khov heev, muaj sia nyob rau ntau txhiab xyoo hauv cov xwm txheej zoo. Tsis ntev los no, cov kws tshawb fawb tau tshawb fawb txog qhov peev xwm no los ntawm kev sau cov ntaub ntawv hauv DNA ntawm lub ntsis xaum, hauv cov kaus poom ntawm cov xim pleev xim, thiab txawm tias los ntawm kev zais cov ntaub ntawv hauv cov kab mob nyob. Tab sis muaj kev cuam tshuam rau kev siv DNA ua cov ntaub ntawv nqa khoom; kev nyeem ntawv thiab sau nws tseem yog txheej txheem nyuaj thiab qeeb.
"Peb yuav siv lub tswv yim uas tsis qiv cov tswv yim ncaj qha los ntawm biology," hais tias Brian Cafferty, ib tus kws sau ntawv ntawm txoj kev tshawb fawb tshiab. "Xwb, peb tso siab rau cov tswv yim uas muaj rau cov organic thiab analytical chemistry thiab tsim ib txoj hauv kev uas siv cov khoom me me, qis-molecular-yuag molecules los encode cov ntaub ntawv."
Hloov DNA, cov kws tshawb fawb tau siv oligopeptides, cov molecules me me ua los ntawm ntau tus lej ntawm cov amino acids. Lub hauv paus rau qhov nruab nrab cia tshiab yog microplate - lub phaj hlau nrog 384 lub hlwb me me. Kev sib txawv ntawm oligopeptides tau muab tso rau hauv txhua lub xovtooj los encode ib byte ntawm cov ntaub ntawv.
Lub tshuab ua raws li cov txheej txheem binary: yog tias muaj ib qho oligopeptide tam sim no, nws tau nyeem raws li 1, thiab yog tias tsis yog, ces raws li 0. Qhov no txhais tau hais tias cov cai hauv txhua lub xov tooj tuaj yeem sawv cev rau ib tsab ntawv lossis ib pixel ntawm ib daim duab. Tus yuam sij rau kev paub txog qhov twg oligopeptide muaj nyob rau hauv ib lub xovtooj ntawm tes yog nws qhov loj, uas tuaj yeem tau txais los ntawm kev siv lub spectrometer.
Hauv lawv qhov kev sim, cov kws tshawb fawb tuaj yeem sau tseg, khaws thiab nyeem 400 KB ntawm cov ntaub ntawv, suav nrog cov ntawv teev lus qhia, daim duab thiab duab. Raws li pab neeg, qhov nruab nrab sau ceev yog yim ntsis ib ob thiab qhov kev nyeem ntawv ceev yog 20 ntsis ib ob, nrog rau qhov tseeb ntawm 99,9%.
Cov kws tshawb fawb hais tias cov txheej txheem tshiab muaj ntau qhov zoo. Oligopeptides tuaj yeem ruaj khov rau ntau pua lossis ntau txhiab xyoo, ua rau lawv xaiv qhov zoo tshaj plaws rau cov ntaub ntawv khaws cia ntev ntev. Lawv tseem tuaj yeem khaws cov ntaub ntawv ntau dua hauv lub cev me me, muaj peev xwm ntau dua li DNA. Yog li, tag nrho cov ntsiab lus ntawm New York Public Library tuaj yeem khaws cia hauv ib lub teaspoon uas muaj protein ntau.
Lub kaw lus tuaj yeem ua haujlwm nrog ntau hom molecules thiab tuaj yeem sau cov ntaub ntawv sai dua nws cov DNA-raws li cov neeg sib tw, txawm hais tias cov kws tshawb fawb lees paub tias kev nyeem ntawv tuaj yeem qeeb heev. Txawm li cas los xij, thev naus laus zis tuaj yeem txhim kho yav tom ntej nrog cov tswv yim zoo dua, xws li siv cov tshuab luam ntawv inkjet los sau cov ntaub ntawv thiab txhim kho huab hwm coj spectrometers los nyeem nws.
Txoj kev tshawb no tau luam tawm nyob rau hauv ib phau ntawv journal scientific .
Tau qhov twg los: 3d xov.ru