Kubva pakurapa kuora mwoyo kusvika pakuderedza migumisiro yechirwere cheParkinson uye kumutsa varwere vari munharaunda yezvinomera, kukurudzirwa kwehuropi hwemagetsi kune simba guru. Chimwe chidzidzo chitsva chine chinangwa chekudzosera kuderera kwekuziva nekuvandudza ndangariro uye kugona kudzidza. Ongororo yakaitwa nevatsvagiri veBoston University yakaratidza nzira isingapindiki inogona kudzoreredza ndangariro inoshanda muvakuru vakura mumakore avo makumi manomwe kusvika padanho rekuti yaive yakanaka seyavanhu vari mumakore avo makumi maviri.
Zvidzidzo zvakawanda zvekusimudzira huropi zvinoshandisa maelectrodes akaiswa munzvimbo chaidzo dzehuropi kuti abudise mapoinzi emagetsi. Iyi nzira inonzi "yakadzama" kana "yakananga" kukurudzira kwehuropi uye ine zvayakanakira nekuda kwekumisikidzwa kwayo kwemhedzisiro. Zvakadaro, kuunzwa kwemaelectrodes muuropi hakuna zvakunoita, uye zvinongobatanidzwa nedzimwe njodzi dzekuzvimba kana kutapukira kana mashandiro ese akasateverwa.
Imwe nzira ndeyekukurudzira zvisina kunanga uchishandisa nzira isiri-invasive (isina-kuvhiya) kuburikidza nemagetsi ari paganda remusoro, izvo zvinobvumira manipulations akadaro kunyangwe kumba. Iyi ndiyo nzira iyo Rob Reinhart, nyanzvi yezvetsinga dzeBoston University, akasarudza kushandisa mukuedza kuvandudza ndangariro dzavanhu vakura, dzinowanzopera simba nezera.
Kunyanya, zviedzo zvake zvakanangana nendangariro yekushanda, inova mhando yendangariro inobatiswa kana, semuenzaniso, tichirangarira zvekutenga muchitoro chegirosari kana kuedza kutsvaga makiyi emota yedu. Sekureva kwaReinhart, ndangariro yekushanda inogona kutanga kudzikira kubva pazera re30 apo nzvimbo dzakasiyana dzehuropi dzinotanga kurasikirwa nekubatana uye kuita kushoma kuwirirana. Apo patinosvika pamakore makumi matanhatu kana makumi manomwe ezera, kusawirirana uku kunogona kukonzera kuderera kunooneka mukushanda kwepfungwa.
Mumwe musayendisiti akawana nzira yekudzoreredza yakakuvadzwa neural connections. Nzira yacho inobva pazvinhu zviviri zvekushanda kwehuropi. Yekutanga ndeye "kubatanidza," apo mativi akasiyana ehuropi anoitwa mukutevedzana kwakapihwa, senge orchestra yakanyatsorongeka. Yechipiri ndeye "synchronization," uko mitsindo inononoka inozivikanwa se theta rhythms uye yakabatana neiyo hippocampus inowiriraniswa nemazvo. Zvose zviri zviviri izvi zvinodzikira nezera uye zvinokanganisa ndangariro.
Nekuda kwekuyedza kwake, Reinhart akaunganidza boka revechidiki vechidiki mumakore avo makumi maviri, pamwe neboka revakuru vakura mune avo 20s uye 60s. Boka rimwe nerimwe raifanira kupedza nhevedzano yemabasa chaiwo aibatanidza kuona mufananidzo, kumbomira, kutarisa mufananidzo wechipiri, uye ipapo kushandisa ndangariro kuziva misiyano mauri.
Hazvishamisi kuti boka rechidiki rekuedza rakaita zviri nani kupfuura mukuru. Asi ipapo Reinhart akaisa maminetsi makumi maviri neshanu ekukurudzira zvinyoro kune cerebral cortex yevakuru vakuru, nemapurusi akaiswa kune mumwe nemumwe neural circuitry kuti aenderane nenzvimbo yecortex inotarisira kushanda ndangariro. Mushure meizvi, mapoka akaramba achipedzisa mabasa, uye mukaha wekuita basa pakati pavo wakanyangarika. Mhedzisiro yacho yakagara kweinenge 25 maminetsi mushure mekusimudzira. Uyezve, Reinhart akawana kuti yakakwanisa kuvandudza ndangariro kunyangwe muvadiki vakaita zvisina kunaka pamabasa.
βTakaona kuti zvidzidzo zvemakore ekuma20 avo vaiomerwa nokupedza mabasa acho vakakwanisawo kubatsirwa kubva mukurudziro yakafanana,β anodaro Reinhart. "Takakwanisa kuvandudza ndangariro yavo yekushanda kunyangwe vaive vasati vapfuura makore 60 kana 70."
Reinhart anotarisira kuenderera mberi nekudzidza kuti kumutswa kwehuropi kungavandudza sei kushanda kwehuropi hwemunhu, kunyanya kune avo vari kurwara nechirwere cheAlzheimer.
"Izvi zvinovhura mikana mitsva yekutsvaga uye kurapwa," anodaro. "Uye isu tinofara zvikuru pamusoro pazvo."
Chidzidzo chacho chakabudiswa mumagazini Nature Neuroscience.
Source: 3dnews.ru