Isiqalisi uFelix ufuna ukubeka amagciwane ahlelekayo ukuze asize abantu

Manje umhlaba ulwa nezinambuzane ezingabonwa ngeso lenyama, futhi uma zingabhekwa zingabulala izigidi zabantu eminyakeni ezayo. Futhi asikhulumi nge-coronavirus entsha, manje esedonsela ukunakwa, kodwa mayelana namagciwane amelana nemithi elwa namagciwane.

Iqiniso liwukuthi ngonyaka odlule nje abantu abangaphezu kuka-700 emhlabeni wonke babulawa izifo ezibangelwa amagciwane. Uma kungenziwa lutho, lesi sibalo singase sikhuphuke sifinyelele ezigidini eziyishumi ngonyaka ngo-000, ngokombiko we-UN. Inkinga ukusetshenziswa ngokweqile kwama-antibiotic odokotela, abantu, nemfuyo nezolimo. Abantu basebenzisa imithi eminingi kakhulu ukubulala amagciwane amabi asezijwayele.

Kulapho isiqalisi se-biotech u-Felix engena khona evela emzuliswaneni wakamuva wokutshalwa kwezimali we-Y Combinator: Ikholelwa ukuthi inganikeza indlela entsha yokuvimbela ukusabalala kwezifo ezibangelwa amagciwane... kusetshenziswa amagciwane.

Manje, ngesikhathi senhlekelele ye-coronavirus yomhlaba wonke, kubonakala kuyinqaba ukubheka leli gciwane ngendlela enhle, kodwa njengoba umsunguli uRobert McBride echaza, ubuchwepheshe obuyinhloko bukaFelix buvumela ukuthi ibhekise igciwane layo ezindaweni ezithile zamagciwane. Lokhu akugcini nje ngokubulala amagciwane ayingozi, kodwa futhi kungamisa ikhono lawo lokukhula futhi lingazweli.

Kodwa umqondo wokusebenzisa igciwane ukubulala amagciwane awumusha. Ama-bacteriophages, noma amagciwane “angathelela” amagciwane, atholwa okokuqala ngumcwaningi oyiNgisi ngo-1915, futhi ukwelashwa kwe-phage kwezentengiselwano kwaqala e-United States ngawo-1940 ngo-Eli Lilly & Co. Kodwa ngasikhathi sinye, kwavela ama-antibiotic alula futhi asebenza kangcono, futhi ososayensi baseNtshonalanga babonakala bewuyekile lo mbono isikhathi eside.

UMnu McBride uqinisekile ukuthi inkampani yakhe ingenza ukwelashwa kwe-phage kube ithuluzi lezokwelapha elisebenzayo. UFeliksi usesihlolile kakade isixazululo sakhe neqembu lokuqala labantu abangu-10 ukukhombisa ukuthi le ndlela isebenza kanjani.

“Singakwazi ukuthuthukisa izindlela zokwelapha ngesikhathi esincane nangemali encane, futhi sesiyazi ukuthi izindlela zokwelapha zethu zingasebenza kubantu,” kusho uRobert McBride. "Siphikisa ngokuthi indlela yethu, eyenza amagciwane aphinde azwele kuma-antibiotic endabuko, ingaba yindlela yokwelapha yokuqala."

UFelix uhlela ukuqala ukwelapha izifo ezibangelwa amagciwane kubantu abane-cystic fibrosis, njengoba lezi ziguli ngokuvamile zidinga ukusakazwa okungapheli kwemithi elwa namagciwane ukulwa nezifo zamaphaphu. Isinyathelo esilandelayo ukwenza uhlolo oluncane lomtholampilo lwabantu abangu-30, bese, ngokuvamile ngemodeli yocwaningo nentuthuko, uhlolo olukhulu lwabantu ngaphambi kwemvume ye-FDA. Kuzothatha isikhathi eside, kodwa uMnu McBride uthemba ukuthi indlela yabo yegciwane ehlelekayo izosiza ukulwa nokwanda kokumelana nama-antibiotic kumagciwane.

“Siyazi ukuthi inkinga yokungazweli ngama-antibiotic inkulu manje futhi izoba yimbi kakhulu,” kusho yena. "Sinesixazululo esihle kakhulu sezobuchwepheshe kule nkinga, futhi siyazi ukuthi ukwelashwa kwethu kungasebenza." Sifuna ukufaka isandla ekusaseni lapho lezi zifo zingabulali abantu abangaphezu kwezigidi ezingu-10 ngonyaka, ikusasa esilikhathalelayo. "

Source: 3dnews.ru